Bromide

Bromide

SCHEMBL7100724

C[S+](C)Cc1ccc(Cl)cc1.[Br-]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHKA known ✓ P35790 1/20 0.36
IDO1 P14902 3/20 0.44
SLC6A2 P23975 2/20 0.41
SLC6A3 Q01959 2/20 0.41
TAAR1 Q96RJ0 2/20 0.41
SLC6A4 P31645 2/20 0.41
HTR2A P28223 1/20 0.41
HRH1 P35367 1/20 0.41
HTR2B P41595 1/20 0.41
CHRNA4 P43681 1/20 0.41
LMNA P02545 1/20 0.40
CYP2A6 P11509 1/20 0.40
AGXT P21549 2/20 0.39
AOC3 Q16853 1/20 0.39
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAOB P27338 1/20 0.35
PYCR1 P32322 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7105383 0.97 IDO1 (0.46) IDO1SLC6A2SLC6A3TAAR1SLC6A4
Hydrochloric Acid SCHEMBL8756281 0.95 IDO1 (0.44) IDO1SLC6A2SLC6A3TAAR1SLC6A4
Hydrochloric Acid SCHEMBL8990690 0.81 KDM4E (0.32) KDM4EALDH1A1
SCHEMBL8757358 0.79 CYP1A2 (0.38) IDO1TAAR1LMNAMEN1KMT2A
SCHEMBL19649630 0.78 IDO1 (0.42) IDO1SLC6A2SLC6A3TAAR1SLC6A4
SCHEMBL9490107 0.76 IDO1 (0.50) IDO1SLC6A2SLC6A3TAAR1SLC6A4
SCHEMBL196856 0.72 IDO1 (0.46) IDO1SLC6A2SLC6A3TAAR1SLC6A4
SCHEMBL8720270 0.72
SCHEMBL13146728 0.72 CYP1A2 (0.43) IDO1SLC6A2SLC6A3TAAR1SLC6A4
Bromide SCHEMBL9333268 0.70 KDM4E (0.52) IDO1SLC6A2SLC6A3TAAR1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0974595-B1 PROCESS FOR PRODUCING BORON COMPOUNDS SHOWA DENKO KK (JP) 2003-10-01 EP disclosed
EP-0922708-B1 Production method of borate compounds SHOWA DENKO KK (JP) 2003-05-14 EP disclosed
US-6140537-A REACTING AN ORGANIC OXYBORON COMPOUND WITH LITHIUM, MAGNESIUM, OR COMPOUND THEREOF; FORMING BORON ANION COMPOUND; ION EXCHANGING SHOWA DENKO K.K. (JP) 2000-10-31 US disclosed
EP-0974595-A1 PROCESS FOR PRODUCING BORON COMPOUNDS Showa Denko Kabushiki Kaisha (JP) 2000-01-26 EP disclosed
US-6002044-A REACTING A LITHIUM OR MAGNEISIUM, A HALIDE AND A BORONATE PRECURSOR OBTAINED IN A FIRSST SIMILAR STEP USING A BORIDE; ADDING AN ONIIUM HALIDE TO THE METAL BORATE; PURITY SHOWA DENKO K.K. (JP) 1999-12-14 US disclosed
EP-0922708-A2 Production method of borate compounds SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-06-16 EP disclosed