Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105383 | 0.83 | IDO1 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL8720270 | 0.83 | — | — | |
| Bromide SCHEMBL7100724 | 0.81 | IDO1 (0.44) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL30093040 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TDP1 | |
| Fluoride Ion SCHEMBL10938266 | 0.79 | TP53 (0.46) | KDM4EALDH1A1TDP1 | |
| SCHEMBL30200215 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1 | |
| Bromide SCHEMBL7101771 | 0.75 | CYP2A6 (0.56) | ALDH1A1 | |
| SCHEMBL1135134 | 0.70 | TP53 (0.37) | KDM4EALDH1A1TDP1 | |
| Acetic Acid SCHEMBL11528727 | 0.69 | CES2 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL6765639 | 0.64 | IDO1 (0.44) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3064354-A | — | — | None | — | — | JP | disclosed |
| JP-63277229-A | — | — | None | — | — | JP | disclosed |
| US-5520849-A | Electrically conductive polymer composition | THE DOW CHEMICAL COMPANY | 1996-05-28 | — | — | US | disclosed |
| EP-0261991-B1 | Method for forming fine patterns of conjugated polymers | SUMITOMO CHEMICAL CO (JP) | 1995-03-15 | — | — | EP | disclosed |
| JP-H0364354-A | CONDUCTIVE FILM AND ITS PRODUCTION | ASAHI CHEM IND CO LTD | 1991-03-19 | — | — | JP | disclosed |
| US-4816383-A | Method for forming fine patterns of conjugated polymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-03-28 | — | — | US | disclosed |
| JP-S63277229-A | PRODUCTION OF POLYPHENYLENE VINYLENE THIN FILM | MATSUSHITA ELECTRIC IND CO LTD | 1988-11-15 | — | — | JP | disclosed |
| EP-0261991-A2 | Method for forming fine patterns of conjugated polymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-30 | — | — | EP | disclosed |
| JP-H00364354-A | — | — | 0001-01-01 | — | — | JP | disclosed |