Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 5/20 | 0.39 |
| ▸ | HTR1B | P28222 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099852 | 1.00 | HTR1D (0.39) | HTR1DHTR1BKMT2AHTR1AHTR2A | |
| SCHEMBL6666419 | 0.73 | HSD17B3 (0.53) | KMT2AHSD17B3MEN1ALDH1A1MAPT | |
| SCHEMBL13085731 | 0.72 | HSD17B3 (0.62) | KMT2AHSD17B3MEN1ALDH1A1MAPT | |
| SCHEMBL17192796 | 0.72 | HSD17B3 (0.51) | KMT2AHSD17B3MEN1ALDH1A1MAPT | |
| SCHEMBL27566212 | 0.71 | HSD17B3 (0.51) | KMT2AHSD17B3MEN1ALDH1A1MAPT | |
| SCHEMBL27663680 | 0.71 | NPC1 (0.53) | HSD17B3THRATHRB | |
| SCHEMBL31494618 | 0.71 | HTR1D (0.46) | HTR1DHTR1BKMT2AHTR1AHTR2A | |
| SCHEMBL7100856 | 0.70 | NAAA (0.47) | — | |
| SCHEMBL7099850 | 0.70 | NAAA (0.47) | — | |
| SCHEMBL9748000 | 0.70 | HSD17B3 (0.49) | KMT2AHSD17B3MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| US-5672598-A | MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |