Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998337 | 0.73 | — | — | |
| SCHEMBL998336 | 0.73 | — | — | |
| SCHEMBL8805015 | 0.72 | MEN1 (0.51) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5724533 | 0.67 | MAOB (0.45) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5550066 | 0.67 | KMT2A (0.50) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2061145 | 0.67 | NPC1 (0.54) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6682212 | 0.66 | NQO2 (0.53) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30408678 | 0.66 | NQO2 (0.53) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL20511418 | 0.66 | MEN1 (0.62) | CYP2C19POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28293274 | 0.65 | ALDH1A1 (0.43) | CYP2C19POLBALDH1A1MAOBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292608-A2 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING SAME, AND USES | L'OREAL (FR) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001094381-A2 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING SAME, AND USES | L'OREAL (FR) | 2001-12-13 | — | — | WO | disclosed |