⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998337 | 1.00 | — | — | |
| SCHEMBL19715986 | 0.88 | — | — | |
| SCHEMBL995684 | 0.83 | KMT2A (0.42) | — | |
| SCHEMBL995682 | 0.83 | KMT2A (0.42) | — | |
| SCHEMBL5002591 | 0.73 | — | — | |
| SCHEMBL7100895 | 0.73 | CYP2C19 (0.43) | — | |
| SCHEMBL8805015 | 0.70 | MEN1 (0.51) | — | |
| SCHEMBL2061458 | 0.67 | ALDH1A1 (0.49) | — | |
| SCHEMBL312143 | 0.67 | ITGA4 (0.47) | — | |
| SCHEMBL3398769 | 0.67 | CA2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998933-B2 | Process for treating the skin comprising applying to the skin at least one composition comprising at least one N-aminoacylamide | L'OREAL S.A. (FR) | 2011-08-16 | — | — | US | claimed |
| US-20110021438-A1 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING THEM AND USES THEREOF | L'OREAL S.A. (FR) | 2011-01-27 | — | — | US | claimed |
| US-20080293962-A1 | Novel compounds of the N-acylamino amide family compositions comprising them and uses thereof | L'OREAL S.A. (FR) | 2008-11-27 | — | — | US | claimed |
| US-7419970-B2 | Aging resistance; controlling skin elasticity; example: ethyl {2-[acetyl(3-trifluoromethyl-phenyl)amino]-3-methylbutyrylamino}acetate; of slowing down the degradation activity of the elastic fibres of the intercellular spaces, may make it possible to reduce this phenomenon of accelerated ageing of skin | L'OREAL (FR) | 2008-09-02 | — | — | US | claimed |
| US-20060211659-A9 | Novel compounds of the N-acylamino amide family, compositions comprising them and uses thereof | DALKO MARIA | 2006-09-21 | — | — | US | claimed |
| US-6987128-B2 | Compounds of the N-acylamino amide family, compositions comprising same, and uses | L'OREAL S.A. (FR) | 2006-01-17 | — | — | US | claimed |
| US-20050187197-A1 | Novel compounds of the N-acylamino amide family, compositions comprising them and uses thereof | DALKO MARIA (FR) | 2005-08-25 | — | — | US | claimed |
| EP-1292608-B1 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING SAME, AND USES | OREAL (FR) | 2004-07-21 | — | — | EP | claimed |
| US-20030152600-A1 | Novel compounds of the n-acylamino-amide-family, cpmpositions comprising same, and uses | L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | claimed |
| US-7998933-B2 | Process for treating the skin comprising applying to the skin at least one composition comprising at least one N-aminoacylamide | L'OREAL S.A. (FR) | 2011-08-16 | — | — | US | disclosed |
| US-20110021438-A1 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING THEM AND USES THEREOF | L'OREAL S.A. (FR) | 2011-01-27 | — | — | US | disclosed |
| US-7786321-B2 | Compounds of the N-acylamino amide family compositions comprising them and uses thereof | L'OREAL S.A. (FR) | 2010-08-31 | — | — | US | disclosed |
| US-20080293962-A1 | Novel compounds of the N-acylamino amide family compositions comprising them and uses thereof | L'OREAL S.A. (FR) | 2008-11-27 | — | — | US | disclosed |
| US-7419970-B2 | Aging resistance; controlling skin elasticity; example: ethyl {2-[acetyl(3-trifluoromethyl-phenyl)amino]-3-methylbutyrylamino}acetate; of slowing down the degradation activity of the elastic fibres of the intercellular spaces, may make it possible to reduce this phenomenon of accelerated ageing of skin | L'OREAL (FR) | 2008-09-02 | — | — | US | disclosed |
| US-20060211659-A9 | Novel compounds of the N-acylamino amide family, compositions comprising them and uses thereof | DALKO MARIA | 2006-09-21 | — | — | US | disclosed |
| US-6987128-B2 | Compounds of the N-acylamino amide family, compositions comprising same, and uses | L'OREAL S.A. (FR) | 2006-01-17 | — | — | US | disclosed |
| US-20050187197-A1 | Novel compounds of the N-acylamino amide family, compositions comprising them and uses thereof | DALKO MARIA (FR) | 2005-08-25 | — | — | US | disclosed |
| EP-1292608-B1 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING SAME, AND USES | OREAL (FR) | 2004-07-21 | — | — | EP | disclosed |
| US-20030152600-A1 | Novel compounds of the n-acylamino-amide-family, cpmpositions comprising same, and uses | L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |