SCHEMBL7100985

SCHEMBL7100985

O=C(Nc1cccc(-n2nnnc2S)c1)c1ccccc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 3/20 0.51
FADS1 O60427 1/20 0.51
MEN1 O00255 7/20 0.49
KMT2A Q03164 7/20 0.49
KDM4E B2RXH2 3/20 0.49
LMNA P02545 3/20 0.49
HPGD P15428 2/20 0.49
TP53 P04637 2/20 0.49
HTT P42858 2/20 0.49
HSD17B10 Q99714 2/20 0.49
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
TERT O14746 1/20 0.46
ALDH1A1 P00352 1/20 0.45
POLB P06746 2/20 0.45
ALOX15 P16050 5/20 0.44
GAA P10253 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10530651 0.88 MEN1 (0.51) MEN1KMT2AKDM4ELMNAHTT
SCHEMBL1122642 0.84 F10 (0.41) FADS1MEN1KMT2ANPC1RAB9A
SCHEMBL5669641 0.84 POLB (0.54) MEN1KMT2AKDM4EHPGDTP53
SCHEMBL6546825 0.84 F10 (0.41) FADS1MEN1KMT2ANPC1RAB9A
SCHEMBL7563729 0.84 F10 (0.41) FADS1MEN1KMT2ANPC1RAB9A
SCHEMBL7559792 0.83 F10 (0.40) FADS1MEN1KMT2ANPC1RAB9A
Potassium SCHEMBL6317761 0.83 F10 (0.40) FADS1MEN1KMT2ANPC1RAB9A
Potassium Ion SCHEMBL6546819 0.83 F10 (0.41) MEN1KMT2AKDM4ENPC1RAB9A
SCHEMBL14498648 0.82 TSHR (0.46) MEN1KMT2ALMNATP53HTT
SCHEMBL8172135 0.81 ALDH1A1 (0.43) LMNATP53NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727707-B1 Mercaptotetrazole transition metal salts for control of dye stain EASTMAN KODAK CO (US) 2003-09-03 EP disclosed
US-6303283-B1 FOR COLOR PRINT FILMS EASTMAN KODAK COMPANY 2001-10-16 US disclosed
US-6083679-A Post sensitization use of iodide in silver chloride emulsion sensitization EASTMAN KODAK COMPANY (US) 2000-07-04 US disclosed
US-5981159-A Photographic material EASTMAN KODAK COMPANY (US) 1999-11-09 US disclosed
EP-0727697-B1 Fine grain bromide emulsions as carriers for photographically useful ingredients added during emulsion finishing EASTMAN KODAK CO (US) 1999-07-28 EP disclosed
EP-0727705-B1 Photographic print material EASTMAN KODAK CO (US) 1998-12-09 EP disclosed
EP-0727697-A2 Fine grain bromide emulsions as carriers for photographically useful ingredients added during emulsion finishing EASTMAN KODAK COMPANY (US) 1996-08-21 EP disclosed
US-5523200-A ADDING SILVER HALIDE FINE GRAIN EMULSION HAVING PHOTOGRAPHICALLY USEFUL COMPOUND ADHERED TO SURFACE TO HIGH CHLORIDE SILVER HALIDE EMULSION DURING CHEMICAL SENSITIZATION HEAT CYCLE EASTMAN KODAK COMPANY (US) 1996-06-04 US disclosed