SCHEMBL5669641

SCHEMBL5669641

O=C(Nc1cccc(-n2nnnc2S)c1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.54
KCNK3 O14649 8/20 0.54
KCNK9 Q9NPC2 6/20 0.54
SIRT1 Q96EB6 1/20 0.49
RAB9A P51151 6/20 0.48
NPC1 O15118 4/20 0.48
HPGD P15428 1/20 0.48
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
TP53 P04637 1/20 0.47
KDM4E B2RXH2 1/20 0.45
NLRP3 Q96P20 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5829495 0.89 RAB9A (0.49) POLBKCNK3KCNK9RAB9ANPC1
SCHEMBL5829094 0.89 KCNK3 (0.48) POLBKCNK3RAB9ANPC1HPGD
SCHEMBL5829255 0.88 KCNK3 (0.58) POLBKCNK3KCNK9RAB9ANPC1
SCHEMBL5829149 0.87 NPC1 (0.53) POLBRAB9ANPC1MEN1KMT2A
SCHEMBL14498648 0.87 TSHR (0.46) POLBSIRT1RAB9ANPC1MEN1
SCHEMBL8172135 0.87 ALDH1A1 (0.43) POLBRAB9ANPC1TP53
SCHEMBL10530651 0.87 MEN1 (0.51) POLBRAB9ANPC1MEN1KMT2A
SCHEMBL5828107 0.86 NPC1 (0.57) POLBKCNK3KCNK9RAB9ANPC1
SCHEMBL5829189 0.86 RAB9A (0.51) POLBSIRT1RAB9ANPC1MEN1
SCHEMBL5829567 0.85 MEN1 (0.50) POLBRAB9ANPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10752782-B2 Radiation curable compositions AGFA NV (BE) 2020-08-25 US disclosed
US-20200047466-A1 LAMINATED SAFETY GLASS AGFA GRAPHICS NV (BE) 2020-02-13 US disclosed
US-10549508-B2 Laminated safety glass AGFA NV (BE) 2020-02-04 US disclosed
US-20170355858-A1 RADIATION CURABLE COMPOSITIONS AGFA NV (BE) 2017-12-14 US disclosed
US-20160303831-A1 LAMINATED SAFETY GLASS AGFA NV (BE) 2016-10-20 US disclosed
WO-2016096719-A1 RADIATION CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2016-06-23 WO disclosed
EP-2883694-A1 Laminated Safety Glass AGFA GRAPHICS NV (BE) 2015-06-17 EP disclosed
US-7455959-B2 Photographic element containing a speed-enhancing compound EASTMAN KODAK COMPANY (US) 2008-11-25 US disclosed
US-20080248433-A1 PHOTOGRAPHIC ELEMENT CONTAINING A SPEED-ENHANCING COMPOUND NPEC INC. 2008-10-09 US disclosed
US-7354701-B2 Photographic element with speed-enhancing compound EASTMAN KODAK COMPANY (US) 2008-04-08 US disclosed
EP-0727707-A1 Mercaptotetrazole transition metal salts for control of cyan stain EASTMAN KODAK COMPANY (US) 1996-08-21 EP disclosed
EP-0727697-A2 Fine grain bromide emulsions as carriers for photographically useful ingredients added during emulsion finishing EASTMAN KODAK COMPANY (US) 1996-08-21 EP disclosed
US-5543281-A PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (US) 1996-08-06 US disclosed
EP-0718679-A1 Cubical silver iodochloride emulsions, processes for their preparation and photographic print elements EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
US-5523200-A ADDING SILVER HALIDE FINE GRAIN EMULSION HAVING PHOTOGRAPHICALLY USEFUL COMPOUND ADHERED TO SURFACE TO HIGH CHLORIDE SILVER HALIDE EMULSION DURING CHEMICAL SENSITIZATION HEAT CYCLE EASTMAN KODAK COMPANY (US) 1996-06-04 US disclosed
US-4415650-A VACUUM DEPOSITING AN ORGANIC AND AN INORGANIC COMPOUND ON A SUPPORT; THERMOSENSITIVITY; LASERS FUJI PHOTO FILM CO., LTD. (JP) 1983-11-15 US disclosed
US-4286045-A A SUPPORT HAVING A LAYER OF A CHALCOGENIDE OF GERMANIUM DOPED WITH SILVER OR COPPER; STABILITY; LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1981-08-25 US disclosed
US-4198237-A GERMANIUM SULFIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-04-15 US disclosed
US-4197124-A SILVER OR COPPER AND SULFUR, SELENIUM OR TELLURIUM0 FUJI PHOTO FILM CO., LTD. (JP) 1980-04-08 US disclosed
US-4177072-A HYDROPHILIC AND OLEOPHILIC AREAS FUJI PHOTO FILM CO., LTD. (JP) 1979-12-04 US disclosed