Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.70 |
| ▸ | CCND1 | P24385 | 2/20 | 0.70 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198405 | 0.89 | SIRT2 (0.60) | CDK4CCND1SIRT2SIRT1MAPT | |
| SCHEMBL29596117 | 0.79 | SIRT2 (0.63) | CDK4CCND1SIRT2SIRT1ALDH1A1 | |
| SCHEMBL20624204 | 0.79 | SIRT2 (0.63) | CDK4CCND1SIRT2SIRT1GSK3B | |
| SCHEMBL8317402 | 0.79 | SIRT2 (0.63) | CDK4CCND1SIRT2SIRT1HTR6 | |
| SCHEMBL20624179 | 0.79 | SIRT2 (0.63) | CDK4CCND1SIRT2SIRT1ALDH1A1 | |
| SCHEMBL7825953 | 0.78 | SIRT2 (0.72) | CDK4CCND1SIRT2SIRT1GSK3B | |
| SCHEMBL9085267 | 0.77 | CDK4 (0.87) | CDK4CCND1SIRT2GSK3BPDGFRB | |
| SCHEMBL7257596 | 0.77 | CDK4 (0.61) | CDK4CCND1MAPTALDH1A1KDM4E | |
| SCHEMBL30958473 | 0.75 | SIRT2 (1.00) | CDK4CCND1SIRT2SIRT1MAPT | |
| SCHEMBL3945882 | 0.75 | SIRT2 (1.00) | CDK4CCND1SIRT2SIRT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769555-B1 | GENE CODING FOR GLYCOSYLTRANSFERASE AND USE THEREOF | BANYU PHARMA CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-RE37206-E1 | FOR GLYCOSYLATING INDOLOPYRROLOCARBAZOLE DERIVATIVES CONVENIENTLY AND ECONOMICALLY | BANYU PHARMACEUTICAL CO, LTD (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0602597-B1 | Process for preparation of indolopyrrolocarbazole derivatives | BANYU PHARMA CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| US-5861293-A | GLYCOSYLATE INDOLOPYRROLOCARBAZOLE DERIVATIVES CONVENIENTLY AND ECONOMICALLY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-19 | — | — | US | disclosed |
| US-5643760-A | GLYCOSYLATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0769555-A1 | GENE CODING FOR GLYCOSYLTRANSFERASE AND USE THEREOF | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-04-23 | — | — | EP | disclosed |
| US-5437996-A | An actinomyces for glycosylation; antitumor agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| EP-0602597-A2 | Process for preparation of indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |