Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.79 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15221577 | 0.89 | IDO1 (0.79) | IDO1ALOX12MLKLGAAL3MBTL1 | |
| SCHEMBL4921708 | 0.89 | IDO1 (1.00) | IDO1ALOX12MLKLGAAL3MBTL1 | |
| SCHEMBL15294554 | 0.88 | ALOX12 (0.73) | IDO1ALOX12MLKLGAAL3MBTL1 | |
| SCHEMBL29537224 | 0.85 | IDO1 (0.72) | IDO1ALOX12MLKLGAAL3MBTL1 | |
| SCHEMBL250817 | 0.85 | IDO1 (0.72) | IDO1ALOX12MLKLGAAL3MBTL1 | |
| SCHEMBL19425511 | 0.85 | IDO1 (0.85) | IDO1ALOX12MLKLGAAL3MBTL1 | |
| SCHEMBL19425618 | 0.85 | IDO1 (0.85) | IDO1ALOX12MLKLGAAL3MBTL1 | |
| SCHEMBL2673705 | 0.85 | IDO1 (0.72) | IDO1ALOX12MLKLGAAL3MBTL1 | |
| SCHEMBL2674618 | 0.85 | IDO1 (0.72) | IDO1ALOX12MLKLGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL29537578 | 0.84 | IDO1 (0.70) | IDO1ALOX12MLKLGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317445-A2 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS | ANORMED INC. (CA) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002022600-A2 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS | ANORMED INC. (CA) | 2002-03-21 | — | — | WO | disclosed |