Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19425618 | 0.92 | IDO1 (0.85) | IDO1GAAL3MBTL1ALOX12ALDH1A1 | |
| SCHEMBL19425511 | 0.92 | IDO1 (0.85) | IDO1GAAL3MBTL1ALOX12ALDH1A1 | |
| SCHEMBL15221577 | 0.89 | IDO1 (0.79) | IDO1GAAL3MBTL1ALOX12ALDH1A1 | |
| SCHEMBL16376072 | 0.89 | IDO1 (0.79) | IDO1GAAL3MBTL1ALOX12ALDH1A1 | |
| SCHEMBL7101160 | 0.89 | IDO1 (0.79) | IDO1GAAL3MBTL1ALOX12ALDH1A1 | |
| SCHEMBL7946544 | 0.88 | IDO1 (0.78) | IDO1GAAL3MBTL1ALOX12ALDH1A1 | |
| SCHEMBL12858901 | 0.84 | IDO1 (0.72) | IDO1GAAL3MBTL1ALOX12ALDH1A1 | |
| SCHEMBL15294554 | 0.84 | ALOX12 (0.73) | IDO1GAAL3MBTL1ALOX12ALDH1A1 | |
| SCHEMBL2674618 | 0.84 | IDO1 (0.72) | IDO1GAAL3MBTL1ALOX12ALDH1A1 | |
| SCHEMBL2673705 | 0.84 | IDO1 (0.72) | IDO1GAAL3MBTL1ALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829634-B | A kind of thirty-two nucleus copper complex and preparation method thereof | 山西大学 | 2016-09-28 | — | — | CN | claimed |
| EP-3318561-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2021-12-22 | — | — | EP | disclosed |
| CN-104829634-B | A kind of thirty-two nucleus copper complex and preparation method thereof | 山西大学 | 2016-09-28 | — | — | CN | disclosed |
| CN-104829634-A | Tridodenuclear copper complex and preparation method thereof | UNIV SHANXI | 2015-08-12 | — | — | CN | disclosed |
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | EFREMOV IVAN | 2008-11-13 | — | — | US | disclosed |
| US-20050020654-A1 | Novel PPAR agonists, pharmaceutical compositions and uses thereof | BETHESDA PHARMACEUTICALS, INC. | 2005-01-27 | — | — | US | disclosed |
| WO-2004082621-A2 | NOVEL PPAR AGONISTS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BETHESDA PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | WO | disclosed |
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020654-A1 | Novel PPAR agonists, pharmaceutical compositions and uses thereof | PPARG, PPARD, PPARA | IDO1 1134/4885GAA 1820/4885L3MBTL1 4796/4885 |
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | PAICS, TMBIM6, ABCG2 | IDO1 2062/4885GAA 44/4885L3MBTL1 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.