SCHEMBL710125

SCHEMBL710125

C1=CCC2=Cc3ccccc3C2=C1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.34
DRD2 P14416 2/20 0.32
DRD4 P21917 2/20 0.32
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30502984 1.00 PTGS2 (0.34) PTGS2DRD2DRD4CDC25ACDC25B
SCHEMBL27800017 0.98 PTGS2 (0.33) PTGS2DRD2DRD4CDC25ACDC25B
SCHEMBL3707104 0.86 CDC25B (0.41) PTGS2CDC25ACDC25B
SCHEMBL5310650 0.78 CDC25B (0.40) CDC25ACDC25B
SCHEMBL15609785 0.77 DRD2 (0.33) DRD2DRD4
SCHEMBL28242714 0.75 PARP11 (0.35)
SCHEMBL23242503 0.73
SCHEMBL30626777 0.72
SCHEMBL28006187 0.72
SCHEMBL19664009 0.72 PTGS2 (0.37) PTGS2DRD2DRD4CDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111718281-A Synthetic structural unit for preparing material for organic electroluminescent device 默克专利有限公司 2020-09-29 CN claimed
CN-108863984-A For detecting Mg2+、Fe3+、Cu2+Azacrown ether containing sulfur-fluorenes schiff bases fluorescent molecular probe and preparation method 德州学院 2018-11-23 CN claimed
CN-108148001-A Aryl imidazoles, preparation method and its dark blue photoelectricity electroluminescence device of hexyl substitution-fluorenes modification 广东工业大学 2018-06-12 CN claimed
US-9718764-B2 Synthetic building blocks for the production of materials for organic electroluminescence devices MERCK PATENT GMBH (DE) 2017-08-01 US claimed
EP-2485750-B1 PEPTIDE-BASED MYELOPEROXIDASE INHIBITORS FOR USE IN THERAPY MEDICAL COLLEGE WISCONSIN INC (US) 2017-05-17 EP claimed
CN-103554505-B Terpyridyl-fluorenes metal hybrid polymkeric substance and the electrochromic device containing this polymkeric substance UNIVERSITY OF SCIENCE AND TECHNOLOGY OF SUZHOU (CN) 2016-04-20 CN claimed
CN-105073709-A Synthetic structural unit for preparing material for organic electroluminescent device MERCK PATENT GMBH 2015-11-18 CN claimed
EP-1771473-B1 APOLIPOPROTEIN A1 MIMETICS AND USES THEREOF TUFTS COLLEGE (US) 2012-12-26 EP claimed
CN-101613462-B Quinoxaline-benzothiadiazole-fluorene polymer and synthesis method and application of organic electroluminescent material with pure green emitted light thereof SHANGHAI INST ORGANIC CHEM 2011-09-14 CN claimed
CN-101613462-A The polymkeric substance of one class quinoxaline-diazosulfide-fluorenes, synthetic and have an application of the electroluminescent organic material of pure green emitted SHANGHAI INST ORGANIC CHEM 2009-12-30 CN claimed
JP-2009545018-A 2009-12-17 JP claimed
EP-2047305-A1 ORIENTED POLYMERIC SHEETS EXHIBITING DICHROISM AND ARTICLES CONTAINING THE SAME TRANSITIONS OPTICAL, INC. (US) 2009-04-15 EP claimed
WO-2008111995-A1 ORIENTED POLYMERIC SHEETS EXHIBITING DICHROISM AND ARTICLES CONTAINING THE SAME TRANSITIONS OPTICAL, INC. (US) 2008-09-18 WO claimed
US-5958930-A TREATING CANCER, AND SECONDARY INFECTIONS CAUSED BY PNEUMOCYSTIS CARINII AND TOXOPLASMOSIS GONDII IN IMMUNOCOMPROMISED PATIENTS. DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) 1999-09-28 US claimed
US-5017724-A Antihypoxic, CNS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-05-21 US claimed
EP-0267024-B1 HYDROFLUORENE DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-05-02 EP claimed
EP-0267024-A2 Hydrofluorene derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-05-11 EP claimed
CN-118159623-A Boron-and nitrogen-containing heterocyclic compounds for organic electroluminescent devices 默克专利有限公司 2024-06-07 CN disclosed
US-3971804-A ACARICIDES, FUNGICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3966624-A LUBRICANTS SUN OIL COMPANY OF PENNSYLVANIA (US) 1976-06-29 US disclosed