SCHEMBL7101274

SCHEMBL7101274

O=C1C(CP(=O)(O)O)CCN1O

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ENO1 P06733 4/20 0.53
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPT P10636 1/20 0.44
APEX1 P27695 1/20 0.44
ENPP1 P22413 2/20 0.33
ACE P12821 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24504148 1.00 ENO1 (0.53) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL18077424 0.69 ENO1 (1.00) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL169033 0.69 CYP3A4 (0.44) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL23863959 0.69 CYP3A4 (0.44) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL7149110 0.69 ENO1 (0.32) ENO1
SCHEMBL24504147 0.68 ENO1 (0.55) ENO1
SCHEMBL7102157 0.63 ENO1 (0.34) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL18077425 0.63 ENO1 (1.00) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL13074065 0.63 ENO1 (0.47) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL6294033 0.61 ENO1 (0.42) ENO1CYP3A4TSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140952-B1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION BIOAGENCY AG (DE) 2003-09-03 EP disclosed