SCHEMBL7102157

SCHEMBL7102157

NC1C(=O)N(O)CC1CP(=O)(O)O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ENO1 P06733 3/20 0.34
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24504148 0.63 ENO1 (0.53) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL7101274 0.63 ENO1 (0.53) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL7149110 0.59 ENO1 (0.32) ENO1
SCHEMBL24504147 0.58 ENO1 (0.55) ENO1
SCHEMBL11021978 0.56 DPP4 (0.45) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL11027484 0.54 DPP4 (0.42) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL20017713 0.54 MEN1 (0.39)
SCHEMBL21925045 0.52
SCHEMBL11023822 0.51 AADAT (0.30)
SCHEMBL1897868 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140952-B1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION BIOAGENCY AG (DE) 2003-09-03 EP disclosed
EP-1140952-A1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION Jomaa Pharmaka GmbH (DE) 2001-10-10 EP disclosed
WO-2000037477-A1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION JOMAA PHARMAKA GMBH (DE) 2000-06-29 WO disclosed