Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC3R | P41968 | 2/20 | 0.35 |
| ▸ | MC1R | Q01726 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.31 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.31 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.31 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7141000 | 0.99 | MC3R (0.34) | MC3RMC1RPTGER4F2RF2 | |
| SCHEMBL7361838 | 0.95 | PTGER4 (0.35) | MC3RMC1RPTGER4F2RF2 | |
| Hydrochloric Acid SCHEMBL7142554 | 0.94 | PTGER4 (0.35) | MC3RMC1RPTGER4F2RF2 | |
| SCHEMBL7139402 | 0.90 | PTGER4 (0.36) | MC3RMC1RPTGER4F2TPH1 | |
| SCHEMBL7144656 | 0.83 | F2 (0.45) | PTGER4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7104093 | 0.83 | NPSR1 (0.34) | MC3RMC1RPTGER4F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7148146 | 0.82 | F2 (0.46) | PTGER4F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7144181 | 0.82 | NPSR1 (0.34) | MC3RMC1RPTGER4F2 | |
| SCHEMBL7100961 | 0.81 | XIAP (0.35) | PTGER4F2 | |
| SCHEMBL7101675 | 0.80 | PTGER4 (0.35) | PTGER4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |
| WO-1995023609-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |