⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534912 | 0.75 | — | — | |
| SCHEMBL21385228 | 0.70 | — | — | |
| SCHEMBL5963506 | 0.70 | — | — | |
| SCHEMBL710129 | 0.70 | — | — | |
| SCHEMBL10423652 | 0.70 | — | — | |
| SCHEMBL8377720 | 0.70 | — | — | |
| SCHEMBL35355 | 0.70 | — | — | |
| SCHEMBL7204552 | 0.70 | CRBN (0.48) | — | |
| SCHEMBL24755086 | 0.67 | CRBN (0.50) | — | |
| SCHEMBL4231518 | 0.67 | CRBN (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | claimed |
| CN-101104608-B | Solanesol derivative, preparation and application thereof | UNIV HENAN | 2011-05-04 | — | — | CN | claimed |
| US-5703224-A | Antiviral c-nucleoside derivatives | NIPPON SHINYAKU CO. LTD. (JP) | 1997-12-30 | — | — | US | claimed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | claimed |
| CN-108350452-B | Purification of nucleic acids using copper-titanium oxides | 雅培分子公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-110272417-A | 2- methyl-1,8- naphthyridine type compound and the preparation method and application thereof | 五邑大学 | 2019-09-24 | — | — | CN | disclosed |
| US-9487476-B2 | Catechol diethers as potent anti-HIV agents | YALE UNIVERSITY (US) | 2016-11-08 | — | — | US | disclosed |
| US-20140288017-A1 | CATECHOL DIETHERS AS POTENT ANTI-HIV AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-09-25 | — | — | US | disclosed |
| WO-2013056003-A2 | CATECHOL DIETHERS AS POTENT ANTI-HIV AGENTS | YALE UNIVERSITY (US) | 2013-04-18 | — | — | WO | disclosed |
| CN-101765369-A | Mannich base N-oxide drugs | NOVACEA INC | 2010-06-30 | — | — | CN | disclosed |
| US-5703224-A | Antiviral c-nucleoside derivatives | NIPPON SHINYAKU CO. LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5703224-A | Antiviral c-nucleoside derivatives | NIPPON SHINYAKU CO. LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0733630-A4 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU CO LTD (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015964-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU CO., LTD. (JP) | 1995-06-15 | — | — | WO | disclosed |