Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 7/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138323 | 0.84 | HTR7 (0.57) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| SCHEMBL32667521 | 0.84 | HTR7 (0.57) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| SCHEMBL2472212 | 0.84 | HTR7 (0.64) | LMNAHTR7CXCR4HTR1ASLC6A2 | |
| SCHEMBL30616744 | 0.84 | HTR7 (0.64) | LMNAHTR7CXCR4HTR1ASLC6A2 | |
| SCHEMBL7098972 | 0.83 | HTR7 (0.59) | LMNAHTR7CHRM3CXCR4HTR1A | |
| SCHEMBL30963898 | 0.83 | LMNA (0.49) | LMNAHTR7CHRM3CXCR4SIGMAR1 | |
| SCHEMBL7100470 | 0.83 | HTR7 (0.63) | LMNAHTR7CHRM3CXCR4SLC6A2 | |
| SCHEMBL15264723 | 0.81 | KDM4E (0.50) | LMNAHTR7CHRM3HTR1ASIGMAR1 | |
| SCHEMBL30963894 | 0.78 | HTR7 (0.52) | LMNAHTR7CHRM3CXCR4MLNR | |
| SCHEMBL7098276 | 0.78 | LMNA (0.55) | LMNAHTR7CXCR4HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |