Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101876 | 0.84 | MEN1 (0.58) | MEN1KMT2AOPRD1SLC6A4USP2 | |
| SCHEMBL8694125 | 0.81 | MEN1 (0.67) | MEN1KMT2AOPRD1SLC6A4USP2 | |
| SCHEMBL7101320 | 0.80 | MEN1 (0.51) | MEN1KMT2AOPRD1SLC6A4OPRM1 | |
| SCHEMBL7101300 | 0.79 | MEN1 (0.72) | MEN1KMT2AOPRD1SLC6A4USP2 | |
| SCHEMBL12065136 | 0.77 | MEN1 (0.74) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| SCHEMBL1138320 | 0.76 | MEN1 (0.79) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| SCHEMBL1138318 | 0.76 | MEN1 (0.79) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| SCHEMBL16225886 | 0.76 | MEN1 (0.79) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| SCHEMBL2794662 | 0.75 | MEN1 (1.00) | MEN1KMT2AOPRD1SLC6A4USP2 | |
| SCHEMBL219432 | 0.75 | MEN1 (1.00) | MEN1KMT2AOPRD1SLC6A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| EP-0690051-B1 | DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE | AZWELL INC (JP) | 2001-07-18 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5716950-A | NONTOXIC ANTIALLERGEN AND ANTIASTHMATIC HAVING LOW ANTIHISTAMINIC SIDE EFFECTS | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0690051-A1 | DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1996-01-03 | — | — | EP | disclosed |