SCHEMBL7101399

SCHEMBL7101399

CCCCC/C=C(\C(=O)CBr)C(=O)OCCC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.46
FAAH O00519 5/20 0.41
TSHR P16473 2/20 0.37
NAAA Q02083 1/20 0.36
PPARG P37231 6/20 0.33
FABP3 P05413 2/20 0.33
PPARA Q07869 1/20 0.33
ATM Q13315 1/20 0.33
TRPA1 O75762 1/20 0.33
FBP1 P09467 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7101402 1.00 EP300 (0.46) EP300FAAHTSHRNAAAPPARG
SCHEMBL7105155 0.95 EP300 (0.40) EP300FAAHTSHRNAAAATM
SCHEMBL7105156 0.95 EP300 (0.40) EP300FAAHTSHRNAAAATM
SCHEMBL7100789 0.94 FAAH (0.48) EP300FAAHTSHRNAAA
SCHEMBL7104207 0.94 EP300 (0.46) EP300FAAHTSHRNAAAATM
SCHEMBL7100787 0.94 FAAH (0.48) EP300FAAHTSHRNAAA
SCHEMBL7104211 0.94 EP300 (0.46) EP300FAAHTSHRNAAAATM
SCHEMBL7105793 0.91 FAAH (0.44) EP300FAAHTSHRNAAAATM
SCHEMBL7105792 0.91 FAAH (0.44) EP300FAAHTSHRNAAAATM
SCHEMBL7100073 0.89 ATM (0.42) EP300FAAHTSHRNAAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1000939-B1 Producing z-isomer of hydrogen bromide salt of 2-aminothiazole derivative SUMITOMO CHEMICAL CO (JP) 2003-09-17 EP disclosed
US-6403572-B1 REACTING ACID SALT OF A 2-AMINOTHIAZOLE COMPOUND WITH INORGANIC ACID SUMITOMO CHEMICAL CO., LTD. (JP) 2002-06-11 US disclosed
US-20020058818-A1 Producing Z-isomer of hydrogen bromide salt of 2-aminothiazole derivative SUMITOMO CHEMICAL CO., LTD. 2002-05-16 US disclosed
US-6340763-B1 SALT FORMATION AND CRYSTALLIZATION, REACTION OF HALOGENATED COMPOUND AND THIOUREA COMPOUND SUMITOMO CHEMICAL CO., LTD. (JP) 2002-01-22 US disclosed
EP-1000939-A1 Producing z-isomer of hydrogen bromide salt of 2-aminothiazole derivative SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058818-A1 Producing Z-isomer of hydrogen bromide salt of 2-aminothiazole derivative ZYX, H1-0, HAO2 EP300 2578/4885FAAH 4261/4885TSHR 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.