Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.50 |
| ▸ | HTR2B | P41595 | 5/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101418 | 1.00 | HTR2C (0.50) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23995533 | 0.84 | HTR2C (0.50) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2238682 | 0.80 | SLC6A4 (0.47) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2238686 | 0.80 | SLC6A4 (0.47) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL12350471 | 0.80 | SLC6A4 (0.47) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4095337 | 0.75 | DRD2 (0.52) | KDM1AMAOAMAOBDRD2DRD3 | |
| SCHEMBL14602807 | 0.75 | HTR2C (0.68) | HTR2CHTR2BSLC6A4SLC6A3HTR2A | |
| SCHEMBL7959436 | 0.75 | HTR2C (0.68) | HTR2CHTR2BSLC6A4SLC6A3KDM1A | |
| SCHEMBL7959439 | 0.75 | HTR2C (0.68) | HTR2CHTR2BSLC6A4SLC6A3KDM1A | |
| SCHEMBL27033783 | 0.75 | HTR2C (0.70) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | HTR2C 1892/4885HTR2B 1860/4885SLC6A4 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.