Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28710409 | 0.80 | NPC1 (0.38) | SPHK2SPHK1SLC18A2 | |
| SCHEMBL27892163 | 0.79 | ABHD6 (0.47) | — | |
| SCHEMBL1769465 | 0.74 | SMN1; SMN2 (0.48) | SPHK1 | |
| SCHEMBL1287227 | 0.74 | SMN1; SMN2 (0.48) | SPHK1 | |
| SCHEMBL6379511 | 0.74 | SMN1; SMN2 (0.48) | SPHK1 | |
| SCHEMBL28710267 | 0.73 | HRH3 (0.46) | HTR2AHRH3 | |
| Hydrochloric Acid SCHEMBL27721454 | 0.73 | HRH3 (0.38) | SPHK2SPHK1HRH3 | |
| SCHEMBL1697453 | 0.72 | SPHK1 (0.46) | SPHK2SPHK1HRH3 | |
| SCHEMBL7390923 | 0.72 | SPHK1 (0.54) | SPHK2SPHK1 | |
| SCHEMBL28787818 | 0.71 | SIGMAR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140952-B1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | BIOAGENCY AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-1140952-A1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | Jomaa Pharmaka GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037477-A1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | JOMAA PHARMAKA GMBH (DE) | 2000-06-29 | — | — | WO | disclosed |