Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961828 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1LMNAKMT2ACYP1A2 | |
| SCHEMBL7928275 | 0.80 | KDM4E (0.49) | KDM4EMAOBALDH1A1HSD17B10LMNA | |
| SCHEMBL22904 | 0.79 | DRD1 (0.46) | KDM4EMAOBALDH1A1HSD17B10LMNA | |
| SCHEMBL29539883 | 0.79 | DRD1 (0.46) | KDM4EMAOBALDH1A1HSD17B10LMNA | |
| SCHEMBL9324046 | 0.79 | KDM4E (0.45) | KDM4EMAOBALDH1A1HSD17B10LMNA | |
| SCHEMBL3721242 | 0.77 | KDM4E (0.44) | KDM4EMAOBALDH1A1HSD17B10LMNA | |
| SCHEMBL27576691 | 0.77 | SLC6A4 (0.43) | ALDH1A1LMNAMAPT | |
| SCHEMBL3824500 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL16032169 | 0.76 | MAOB (0.43) | KDM4EMAOBALDH1A1HSD17B10LMNA | |
| SCHEMBL30693956 | 0.76 | MAOB (0.43) | KDM4EMAOBALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |