Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29539883 | 1.00 | DRD1 (0.46) | DRD1MAOBMEP1BKMT2ARAB9A | |
| SCHEMBL16032169 | 0.83 | MAOB (0.43) | MAOBKMT2ARAB9ANPC1MAPT | |
| SCHEMBL30693956 | 0.83 | MAOB (0.43) | MAOBKMT2AMAPTLMNACYP1A2 | |
| SCHEMBL2283508 | 0.82 | MEP1B (0.39) | DRD1MEP1BKMT2ARAB9ANPC1 | |
| SCHEMBL2821243 | 0.82 | CES2 (0.50) | MAOBKMT2ARAB9ANPC1MAPT | |
| SCHEMBL2281706 | 0.81 | RAB9A (0.45) | MAOBKMT2ARAB9ANPC1MAPT | |
| SCHEMBL13016953 | 0.79 | DRD1 (0.51) | DRD1KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL7101430 | 0.79 | KDM4E (0.48) | MAOBKMT2AMAPTLMNACYP1A2 | |
| SCHEMBL8384042 | 0.78 | NPC1 (0.49) | MAOBKMT2ARAB9ANPC1MAPT | |
| SCHEMBL1204347 | 0.78 | NPC1 (0.49) | MAOBKMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100391923-C | Alkylcyclohexyl multiple-fluorine biphenyl derivative and its preparation method and uses | UNIV TSINGHUA (CN) | 2008-06-04 | — | — | CN | claimed |
| CN-100372825-C | 3,4-difluoro-2-methoxyl biphenyl derivative and its prepn process and application | UNIV TSINGHUA (CN) | 2008-03-05 | — | — | CN | claimed |
| CN-1847211-A | 3,4-difluoro-2-methoxyl biphenyl derivative and its prepn process and application | UNIV TSINGHUA (CN) | 2006-10-18 | — | — | CN | claimed |
| CN-1762946-A | Alkylcyclohexyl multiple-fluorine biphenyl derivative and its preparation method and uses | UNIV TSINGHUA (CN) | 2006-04-26 | — | — | CN | claimed |
| EP-4685143-A1 | DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF | Vivozon,Inc. (KR) | 2026-01-28 | — | — | EP | disclosed |
| EP-4661964-A1 | COMPOUNDS AS CCR6 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-12-17 | — | — | EP | disclosed |
| US-20250353859-A1 | COMPOUNDS AS CCR6 INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2025-11-20 | — | — | US | disclosed |
| US-12466781-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2025-11-11 | — | — | US | disclosed |
| US-12428411-B2 | Preparation of oxindole derivatives as novel diacylglyceride o-acyltransferase 2 inhibitors | MERCK SHARP & DOHME LLC (US) | 2025-09-30 | — | — | US | disclosed |
| US-12410159-B2 | Preparation of oxindole derivatives as novel diacylglyceride O-acyltransferase 2 inhibitors | MERCK SHARP & DOHME LLC (US) | 2025-09-09 | — | — | US | disclosed |
| US-20250092016-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2025-03-20 | — | — | US | disclosed |
| US-20250059172-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL | NIPPON SHINYAKU CO., LTD. (JP) | 2025-02-20 | — | — | US | disclosed |
| CN-1829697-A | Aryl-heteroaromatic products, compositions containing same and use thereof | AVENTIS PHARMA SA (FR) | 2006-09-06 | — | — | CN | disclosed |
| CN-1762946-A | Alkylcyclohexyl multiple-fluorine biphenyl derivative and its preparation method and uses | UNIV TSINGHUA (CN) | 2006-04-26 | — | — | CN | disclosed |
| EP-1641765-A1 | ARYL-HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF | Aventis Pharma S.A. (FR) | 2006-04-05 | — | — | EP | disclosed |
| EP-1590329-A1 | N-ARYL HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF | Aventis Pharma S.A. (FR) | 2005-11-02 | — | — | EP | disclosed |
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AVENTIS PHARMA S. A. (FR) | 2005-06-16 | — | — | US | disclosed |
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AVENTIS PHARMA S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108685-A1 | ARYL-HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2004-12-16 | — | — | WO | disclosed |
| WO-2004078732-A1 | N-ARYL HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AHR, ARNT, MYC | DRD1 2996/4885MAOB 195/4885MEP1B 2951/4885 |
| US-20250059172-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL | MC5R, CYP3A5, PTGIS | DRD1 1133/4885MAOB 2133/4885MEP1B 618/4885 |
| US-20250092016-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | ACE2, ACE, TMPRSS2 | DRD1 4187/4885MAOB 372/4885MEP1B 1238/4885 |
| US-12466781-B2 | Thyromimetics | TPO, TSHR, CHRM1 | DRD1 833/4885MAOB 574/4885MEP1B 1720/4885 |
| US-12410159-B2 | Preparation of oxindole derivatives as novel diacylglyceride O-acyltransferase 2 inhibitors | DGAT2, DGAT1, MOGAT2 | DRD1 1622/4885MAOB 511/4885MEP1B 4502/4885 |
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AHR, NQO1, ARNT | DRD1 2686/4885MAOB 409/4885MEP1B 1207/4885 |
| US-12428411-B2 | Preparation of oxindole derivatives as novel diacylglyceride o-acyltransferase 2 inhibitors | DGAT2, DGAT1, MOGAT2 | DRD1 1622/4885MAOB 511/4885MEP1B 4502/4885 |
| US-20250353859-A1 | COMPOUNDS AS CCR6 INHIBITORS | CCR6, CCR4, CCR1 | DRD1 1310/4885MAOB 4262/4885MEP1B 1367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.