Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | PDE4A | P27815 | 7/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29609639 | 1.00 | LMNA (0.83) | LMNAPDE4ACYP1A2CYP2C19KMT2A | |
| Simazine SCHEMBL9123386 | 0.91 | LMNA (0.91) | LMNAPDE4ACYP1A2CYP2C19KMT2A | |
| Simazine SCHEMBL9130727 | 0.91 | LMNA (1.00) | LMNAPDE4ACYP1A2CYP2C19KMT2A | |
| Simazine SCHEMBL37774 | 0.91 | LMNA (1.00) | LMNAPDE4ACYP1A2CYP2C19KMT2A | |
| Simazine SCHEMBL8409822 | 0.91 | LMNA (1.00) | LMNAPDE4ACYP1A2CYP2C19KMT2A | |
| Simazine SCHEMBL28076157 | 0.89 | LMNA (0.95) | LMNAPDE4ACYP1A2CYP2C19KMT2A | |
| SCHEMBL14869406 | 0.89 | LMNA (0.61) | LMNAPDE4ACYP1A2CYP2C19KMT2A | |
| SCHEMBL8166873 | 0.89 | LMNA (0.61) | LMNAPDE4ACYP1A2CYP2C19KMT2A | |
| Simazine SCHEMBL23716534 | 0.86 | LMNA (0.91) | LMNAPDE4ACYP1A2CYP2C19KMT2A | |
| Simazine SCHEMBL4731210 | 0.86 | LMNA (0.91) | LMNAPDE4ACYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191774-B | Heterocyclic compound, preparation method and application thereof | 中国药科大学 | 2022-05-24 | — | — | CN | disclosed |
| EP-0751170-B1 | Silicone derivatives, their production and use | CHIBA FLOUR MILLING (JP) | 2003-01-22 | — | — | EP | disclosed |
| CN-1069644-C | Novel silicone derivatives,their production and use | CHIBA FLOUR MILLING (JP) | 2001-08-15 | — | — | CN | disclosed |
| US-5859243-A | AMINOSILICONES HAVING PYRIMIDINYL GROUPS BOUND TO THE AMINO GROUPS; USED TO GEL SILICONE OIL OR TO INCREASE THE VISCOSITY STABLY AND HOMOGENEOUSLY; BASES FOR COSMETICS, DRUGS, INDUSTRIAL MATERIAL; FEEL; TEXTURE | CHIBA FLOUR MILLING CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| US-5712391-A | POLYSILOXANES MODIFIED WITH TRIAZINE GROUPS AND DIAMINE COMPOUNDS FOR COSMETICS | CHIBA FLOUR MILLING CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| CN-1145907-A | Novel silicone derivatives,their production and use | CHIBA FLOUR MILLING (JP) | 1997-03-26 | — | — | CN | disclosed |
| EP-0751170-A2 | Silicone derivatives, their production and use | Chiba Flour Milling Co., Ltd. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-3931165-A | INSECTICIDES, HERBICIDES | BARER SOL J | 1976-01-06 | — | — | US | disclosed |