Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 7/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 5/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472212 | 0.87 | HTR7 (0.64) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| SCHEMBL30616744 | 0.87 | HTR7 (0.64) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| SCHEMBL32667521 | 0.85 | HTR7 (0.57) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| SCHEMBL1138323 | 0.85 | HTR7 (0.57) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| SCHEMBL7097403 | 0.85 | HTR7 (0.62) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| SCHEMBL7098277 | 0.85 | LMNA (0.53) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| SCHEMBL376781 | 0.85 | HTR7 (0.56) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| SCHEMBL30963898 | 0.84 | LMNA (0.49) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| Hydrochloric Acid SCHEMBL30688262 | 0.84 | HTR7 (0.55) | LMNAHTR7CXCR4SIGMAR1MLNR | |
| Hydrochloric Acid SCHEMBL5689236 | 0.84 | HTR7 (0.55) | LMNAHTR7CXCR4SIGMAR1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |