Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416547 | 1.00 | ITGB1 (0.48) | ITGB1ITGA4ITGB7 | |
| Tromethamine SCHEMBL7099740 | 0.95 | ITGB1 (0.44) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7416413 | 0.95 | ITGB1 (0.40) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7105287 | 0.95 | ITGB1 (0.40) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7100811 | 0.94 | ITGB1 (0.44) | ITGB1ITGA4 | |
| SCHEMBL1820303 | 0.94 | ITGB1 (0.44) | ITGB1ITGA4 | |
| SCHEMBL7106468 | 0.94 | ITGB1 (0.41) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7107727 | 0.93 | ITGB1 (0.44) | ITGB1ITGA4 | |
| SCHEMBL7101082 | 0.92 | ITGB1 (0.49) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7102059 | 0.92 | ITGB1 (0.49) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183241-B1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | AVENTIS PHARMA GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6399643-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-06-04 | — | — | US | disclosed |
| EP-1183241-A1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | Aventis Pharma Deutschland GmbH (DE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000069831-A1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-23 | — | — | WO | disclosed |