Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CCR1 | P32246 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 3/20 | 0.47 |
| ▸ | CCR8 | P51685 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16034316 | 0.83 | KDM5A (0.57) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL18579661 | 0.80 | KDM5A (0.60) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL4865471 | 0.79 | PDE10A (0.49) | KDM4ELMNAKDM4CALDH1A1TDP1 | |
| SCHEMBL18579509 | 0.78 | KDM2B (0.62) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL18579672 | 0.76 | KDM4C (0.67) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL18579812 | 0.76 | KDM4C (0.67) | KDM4CNPC1RAB9AKDM5AKDM5B | |
| SCHEMBL18579569 | 0.76 | KDM5B (0.62) | KDM4CSMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL18579762 | 0.76 | KDM5A (0.67) | KDM4EKDM4CSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL16534860 | 0.75 | GRM5 (0.49) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL7100927 | 0.75 | CYP2E1 (0.44) | KDM4CKDM5AKDM5BKDM4AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952157-B1 | 9A, 11B-Dehydro derivatives of 9-oxime-3-keto-6-0-methylerythromycin | PFIZER PROD INC (US) | 2003-06-18 | — | — | EP | claimed |
| US-6482801-B2 | THERAPY FOR BACTERIAL OR PROTOZOA INFECTIONS | PFIZER INC. | 2002-11-19 | — | — | US | claimed |
| US-20010016574-A1 | 9a,11b-dehydro derivatives of 9-oxime-3-keto-6-O- methylerythromycin | WU YONG-JIN (US) | 2001-08-23 | — | — | US | claimed |
| EP-0952157-A1 | 9A, 11B-Dehydro derivatives of 9-oxime-3-keto-6-0-methylerythromycin | Pfizer Products Inc. (US) | 1999-10-27 | — | — | EP | claimed |
| EP-0952157-B1 | 9A, 11B-Dehydro derivatives of 9-oxime-3-keto-6-0-methylerythromycin | PFIZER PROD INC (US) | 2003-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010016574-A1 | 9a,11b-dehydro derivatives of 9-oxime-3-keto-6-O- methylerythromycin | CYP7A1, HSD17B7, CYP51A1 | KDM4E 209/4885LMNA 3343/4885CCR1 829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.