Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 3/20 | 0.45 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846684 | 0.78 | GSK3B (0.52) | CYP2A13SLC2A2KDM4EALDH1A1MAPT | |
| SCHEMBL27538115 | 0.76 | CYP2A13 (0.55) | CYP2A13SLC2A2KDM4EALDH1A1MAPT | |
| SCHEMBL3370971 | 0.70 | DPP4 (0.56) | DPP4NPC1RAB9ACYP3A4 | |
| SCHEMBL5099299 | 0.69 | CYP2A13 (0.48) | CYP2A13SLC2A2KDM4EALDH1A1MAPT | |
| SCHEMBL7857358 | 0.68 | DHFR (0.49) | DPP4MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5082578 | 0.67 | DPP4 (0.48) | DPP4CYP3A4 | |
| SCHEMBL4972403 | 0.66 | CYP2A13 (0.56) | CYP2A13SLC2A2KDM4EALDH1A1MAPT | |
| SCHEMBL3601192 | 0.65 | TSHR (0.44) | CYP2A13SLC2A2DPP4HTTSMN1; SMN2 | |
| SCHEMBL4109682 | 0.64 | CYP2A13 (1.00) | CYP2A13KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL6068869 | 0.64 | CYP2A13 (0.56) | CYP2A13SLC2A2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317433-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020495-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |