Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7106728 | 0.99 | PTGS2 (0.49) | PTGS2TDP1L3MBTL1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7169819 | 0.90 | PTGS2 (0.44) | PTGS2TDP1L3MBTL1DRD2DRD3 | |
| SCHEMBL19719469 | 0.90 | PTGS2 (0.57) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| Naproxcinod SCHEMBL29663794 | 0.90 | PTGS2 (0.57) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL13730523 | 0.90 | PTGS2 (0.57) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| Naproxcinod SCHEMBL1170879 | 0.90 | PTGS2 (0.57) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| Naproxcinod SCHEMBL1448284 | 0.90 | PTGS2 (0.57) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL1245933 | 0.89 | PTGS2 (0.56) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL5604761 | 0.89 | PTGS2 (0.56) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL13730950 | 0.89 | PTGS2 (0.56) | PTGS2TDP1L3MBTL1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000300-A1 | CYCLOOXYGENASE-2 INHIBITORS | NICOX S.A. (FR) | 2003-12-31 | — | — | WO | disclosed |