Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29406417 | 0.84 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1RAB9ACASP1 | |
| SCHEMBL1145034 | 0.84 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1RAB9ACASP1 | |
| Benzophenone SCHEMBL27908043 | 0.84 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| Quinoline SCHEMBL28106687 | 0.83 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1RAB9ACASP1 | |
| Hydrochloric Acid SCHEMBL9691126 | 0.83 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1RAB9ACASP1 | |
| SCHEMBL27268710 | 0.83 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1RAB9ACASP1 | |
| Benzophenone SCHEMBL29065284 | 0.80 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL2524478 | 0.79 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1RAB9ACASP1 | |
| SCHEMBL4517996 | 0.79 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1CASP1CASP7 | |
| SCHEMBL2232014 | 0.79 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1310498-A2 | Pyrazoloquinolinone derivatives as protein kinase C inhibitors | PFIZER INC. (US) | 2003-05-14 | — | — | EP | disclosed |