Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102211 | 0.88 | ALDH1A1 (0.47) | ALDH1A1ESR1TSHRTDP1HCAR2 | |
| SCHEMBL7100499 | 0.84 | ALDH1A1 (0.34) | ALDH1A1ESR1CHRM1TSHRSLC6A2 | |
| SCHEMBL6247104 | 0.83 | ALDH1A1 (0.40) | ALDH1A1ESR1TDP1LMNAMAPT | |
| SCHEMBL16160096 | 0.83 | ALDH1A1 (0.38) | ALDH1A1ESR1CHRM1TSHRSLC6A2 | |
| SCHEMBL7101890 | 0.82 | MAPT (0.36) | ALDH1A1ESR1CHRM1TSHRSLC6A2 | |
| SCHEMBL22591380 | 0.82 | — | — | |
| SCHEMBL4206328 | 0.82 | HCAR2 (0.43) | ALDH1A1ESR1CHRM1TSHRSLC6A2 | |
| SCHEMBL7100979 | 0.81 | MAPT (0.43) | ALDH1A1ESR1CHRM1TSHRSLC6A2 | |
| SCHEMBL7096884 | 0.77 | TSHR (0.42) | ALDH1A1TSHRTDP1LMNAMAPT | |
| SCHEMBL19766426 | 0.76 | ALDH1A1 (0.34) | ALDH1A1ESR1CHRM1TSHRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |