Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 4/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.32 |
| ▸ | PRKACG | P22612 | 3/20 | 0.32 |
| ▸ | PRKACB | P22694 | 3/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.32 |
| ▸ | PRKCG | P05129 | 2/20 | 0.32 |
| ▸ | PRKCB | P05771 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | PRKCH | P24723 | 2/20 | 0.32 |
| ▸ | PRKCI | P41743 | 2/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5880792 | 0.78 | KMT2A (0.38) | SMN1; SMN2TSHRMAPK1KMT2AALDH1A1 | |
| SCHEMBL5880745 | 0.76 | DNMT1 (0.41) | MEN1CYP3A4CYP2D6CYP2C9MAPK1 | |
| SCHEMBL7998562 | 0.73 | DNMT1 (0.38) | LMNADNMT1 | |
| SCHEMBL8007831 | 0.72 | DNMT1 (0.38) | MEN1KMT2AALDH1A1LMNADNMT1 | |
| SCHEMBL5880867 | 0.72 | LMNA (0.39) | MEN1MAPK1KMT2AALDH1A1LMNA | |
| SCHEMBL5880727 | 0.71 | BCHE (0.42) | SMN1; SMN2MEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL5880739 | 0.71 | ALDH1A1 (0.38) | MEN1TSHRKMT2AHTTALDH1A1 | |
| SCHEMBL8008848 | 0.70 | PTGDR2 (0.43) | CYP2C19DNMT1 | |
| SCHEMBL7999810 | 0.69 | DNMT1 (0.38) | DNMT1 | |
| SCHEMBL5880828 | 0.69 | DNMT1 (0.32) | SMN1; SMN2MAPK1ALDH1A1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |