Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872336 | 0.82 | KMT2A (0.80) | EPHX2SMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL1581301 | 0.80 | EPHX2 (0.61) | CYP1A2CYP2C19EPHX2SMN1; SMN2LMNA | |
| SCHEMBL7101800 | 0.77 | CYP1A2 (0.53) | CYP1A2CYP2C19SMN1; SMN2LMNAKMT2A | |
| SCHEMBL8988613 | 0.77 | RORC (0.55) | SMN1; SMN2LMNAKMT2AMEN1GAA | |
| SCHEMBL5469490 | 0.76 | SMN1; SMN2 (0.66) | CYP1A2CYP2C19EPHX2SMN1; SMN2LMNA | |
| SCHEMBL15876305 | 0.76 | KMT2A (0.58) | CYP1A2CYP2C19EPHX2SMN1; SMN2LMNA | |
| SCHEMBL19427446 | 0.76 | EPHX2 (0.80) | CYP2C19EPHX2SMN1; SMN2LMNAHTT | |
| SCHEMBL15758031 | 0.75 | EPHX2 (0.70) | EPHX2SMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL8410450 | 0.75 | LMNA (0.59) | SMN1; SMN2LMNAHTTNPSR1KMT2A | |
| SCHEMBL5443977 | 0.75 | RORC (0.72) | EPHX2SMN1; SMN2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101941-A2 | ALPHA ACYLOXYACETAMIDES FOR KALLIKREIN AND UROKINASE INHIBITION | GENZYME CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |