SCHEMBL7101907

SCHEMBL7101907

NC(c1ccccc1)C1(O)CCCCC1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.40
CHRM1 P11229 2/20 0.40
CHRM3 P20309 2/20 0.40
CHRM4 P08173 1/20 0.40
LMNA P02545 2/20 0.40
DPP4 P27487 2/20 0.39
F2 P00734 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
OPRM1 P35372 2/20 0.39
OPRD1 P41143 2/20 0.39
OPRK1 P41145 2/20 0.39
OPRL1 P41146 2/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7105607 1.00 CHRM2 (0.40) CHRM2CHRM1CHRM3CHRM4LMNA
SCHEMBL4441548 1.00 CHRM2 (0.40) CHRM2CHRM1CHRM3CHRM4LMNA
SCHEMBL1153253 1.00 CHRM2 (0.40) CHRM2CHRM1CHRM3CHRM4LMNA
SCHEMBL4556659 0.98 LMNA (0.41) CHRM2CHRM1CHRM3CHRM4LMNA
SCHEMBL8622210 0.98 LMNA (0.41) CHRM2CHRM1CHRM3CHRM4LMNA
SCHEMBL1153684 0.98 LMNA (0.41) CHRM2CHRM1CHRM3CHRM4LMNA
SCHEMBL6570495 0.94 DPP4 (0.41) CHRM2CHRM1CHRM3LMNADPP4
SCHEMBL1152738 0.94 DPP4 (0.41) CHRM2CHRM1CHRM3LMNADPP4
SCHEMBL16965781 0.94 DPP4 (0.41) CHRM2CHRM1CHRM3LMNADPP4
SCHEMBL18793693 0.90 DPP4 (0.44) LMNADPP4F2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0942010-B1 Transition metal compounds, catalyst components and catalysts for olefin polymerization, and process for producing olefinic polymer SUMITOMO CHEMICAL CO (JP) 2003-06-18 EP disclosed
US-6500909-B2 CONTAINING NICKEL, PALLADIUM, RHODIUM, RUTHENIUM, OR COBALT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-31 US disclosed
US-20010027162-A1 Transition metal compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefinic polymer HIRAHATA WATARU (JP) 2001-10-04 US disclosed
US-6242377-B1 POLYMERIZATION IN PRESENCE OF BISOXAZOLINE WITH NICKEL, COBALT, PALLADIUM, RHODIUM, RUTHENIUM, ALUMINUM AND BORON COMPLEXES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-05 US disclosed
EP-0942010-A1 Transition metal compounds, catalyst components and catalysts for olefin polymerization, and process for producing olefinic polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-15 EP disclosed
US-4155935-A Benzylamine analgesics AMERICAN HOME PRODUCTS CORPORATION (US) 1979-05-22 US disclosed
US-4017637-A Benzylamine analgesics AMERICAN HOME PRODUCTS CORPORATION (US) 1977-04-12 US disclosed
US-3928626-A Benzylamine analgesics AMERICAN HOME PROD 1975-12-23 US disclosed