Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1153684 | 1.00 | LMNA (0.41) | LMNACHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL4556659 | 1.00 | LMNA (0.41) | LMNACHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL1153253 | 0.98 | CHRM2 (0.40) | LMNACHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL4441548 | 0.98 | CHRM2 (0.40) | LMNACHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL7101907 | 0.98 | CHRM2 (0.40) | LMNACHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL7105607 | 0.98 | CHRM2 (0.40) | LMNACHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL1152738 | 0.96 | DPP4 (0.41) | LMNACHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL6570495 | 0.96 | DPP4 (0.41) | LMNACHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL16965781 | 0.96 | DPP4 (0.41) | LMNACHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL18793693 | 0.91 | DPP4 (0.44) | LMNADPP4F2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713880-B1 | Stereoselective reduction of 17-ketosteroids | JENAPHARM GMBH (DE) | 1998-06-10 | — | — | EP | disclosed |
| EP-0713880-A2 | Stereoselective reduction of 17-ketosteroids | JENAPHARM GmbH (DE) | 1996-05-29 | — | — | EP | disclosed |