SCHEMBL710220

SCHEMBL710220

O=C(O)c1cc(Br)c(-c2cc(C(=O)O)c(C(=O)O)cc2Br)cc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.48
FYN P06241 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA3 P07451 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA13 Q8N1Q1 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CA5B Q9Y2D0 1/20 0.47
AKR1C3 P42330 3/20 0.46
AKR1C2 P52895 3/20 0.46
AKR1C1 Q04828 3/20 0.46
AKR1C4 P17516 2/20 0.46
HSD17B10 Q99714 3/20 0.44
TSHR P16473 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17890434 0.86 LCK (0.56) LCKFYNCA12CA1CA2
SCHEMBL71146 0.86 LCK (0.60) LCKFYNCA12CA1CA2
SCHEMBL4626489 0.86 AKR1C4 (0.52) LCKFYNCA12CA1CA2
SCHEMBL11706863 0.83 LCK (0.58) LCKFYNCA12CA1CA2
SCHEMBL28217573 0.83 AKR1C4 (0.50) LCKFYNCA12CA1CA2
Ethylene SCHEMBL11741498 0.81 LCK (0.56) LCKFYNCA12CA1CA2
SCHEMBL71307 0.78 CA12 (0.61) LCKFYNCA12CA1CA2
SCHEMBL31169213 0.77 AKR1C4 (0.50) LCKFYNCA12CA1CA2
SCHEMBL24697741 0.75 KEAP1 (0.45) LCKFYNCA12CA1CA2
Terephthalic Acid SCHEMBL11743717 0.75 TSHR (0.57) LCKFYNCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0698052-B1 NEGATIVE BIREFRINGENT POLYIMIDE FILMS UNIV AKRON (US) 2000-06-14 EP claimed
US-5480964-A CONTROLLING ORIENTATION BY SUBSTITUTION ON AROMATIC BACKBONE THE UNIVERSITY OF AKRON (US) 1996-01-02 US claimed
US-5395918-A Heat resistance, electrical resistance and mechanical properties THE UNIVERSITY OF AKRON (US) 1995-03-07 US claimed
US-9494720-B2 Polarizing film, laminated film, and liquid crystal display NITTO DENKO CORPORATION (JP) 2016-11-15 US disclosed
US-9465253-B2 Liquid crystal display apparatus having excellent viewing angle compensation NITTO DENKO CORPORATION (JP) 2016-10-11 US disclosed
US-20150109564-A1 POLARIZING PLATE WITH AN OPTICAL COMPENSATION LAYER, LIQUID CRYSTAL PANEL, LIQUID CRYSTAL DISPLAY APPARATUS, AND IMAGE DISPLAY APPARATUS USING THE POLARIZING PLATE WITH AN OPTICAL COMPENSATION LAYER NITTO DENKO CORPORATION (JP) 2015-04-23 US disclosed
US-8743319-B2 Liquid crystal panel having several polarizing plates with related light transmittance and liquid crystal display apparatus NITTO DENKO CORPORATION (JP) 2014-06-03 US disclosed
US-8722842-B2 Optical film and image display device NITTO DENKO CORPORATION (JP) 2014-05-13 US disclosed
US-8551284-B2 Polarizing film, laminated film and liquid crystal display NITTO DENKO CORPORATION (JP) 2013-10-08 US disclosed
US-8531630-B2 Liquid crystal panel and liquid crystal display apparatus NITTO DENKO CORPORATION (JP) 2013-09-10 US disclosed
US-8493527-B2 Liquid crystal panel and liquid crystal display apparatus NITTO DENKO CORPORATION (JP) 2013-07-23 US disclosed
EP-1477828-A1 GRADED OPTICAL COMPENSATION FILM, PROCESS FOR PRODUCING THE SAME AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME NITTO DENKO CORPORATION (JP) 2004-11-17 EP disclosed
US-6819382-B2 Method for producing substrate of liquid crystal cell and method for producing liquid crystal panel NITTO DENKO CORPORATION (JP) 2004-11-16 US disclosed
EP-1469328-A1 OPTICAL FILM, MULTILAYER POLARIZATION PLATE, LIQUID CRYSTAL DISPLAY COMPRISING THEM, AND SPONTANEOUS EMISSION DISPLAY NITTO DENKO CORPORATION (JP) 2004-10-20 EP disclosed
US-20040202849-A1 Birefringent optical film, elliptically polarizing plate using the same, and liquid crystal display using the same NITTO DENKO CORPORATION (JP) 2004-10-14 US disclosed
US-20040100599-A1 Method for producing substrate of liquid crystal cell and method for producing liquid crystal panel NITTO DENKO CORPORATION (JP) 2004-05-27 US disclosed
WO-2000045435-A1 POLYIMIDES USED AS MICROELECTRONIC COATINGS THE UNIVERSITY OF AKRON (US) 2000-08-03 WO disclosed
EP-0698052-B1 NEGATIVE BIREFRINGENT POLYIMIDE FILMS UNIV AKRON (US) 2000-06-14 EP disclosed
US-5480964-A CONTROLLING ORIENTATION BY SUBSTITUTION ON AROMATIC BACKBONE THE UNIVERSITY OF AKRON (US) 1996-01-02 US disclosed
US-5395918-A Heat resistance, electrical resistance and mechanical properties THE UNIVERSITY OF AKRON (US) 1995-03-07 US disclosed