Sugi Predict

Sugi Predict / Compounds / SCHEMBL4626489

SCHEMBL4626489

SCHEMBL4626489

O=C(O)c1cc(Br)c(Br)cc1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AKR1C4 P17516 2/20 0.52
▸ AKR1C3 P42330 2/20 0.52
▸ AKR1C2 P52895 2/20 0.52
▸ AKR1C1 Q04828 2/20 0.52
▸ LCK P06239 1/20 0.48
▸ FYN P06241 1/20 0.48
▸ PTPN1 P18031 3/20 0.46
▸ CA12 O43570 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ CA3 P07451 1/20 0.46
▸ CA4 P22748 1/20 0.46
▸ CA6 P23280 1/20 0.46
▸ CA5A P35218 1/20 0.46
▸ CA7 P43166 1/20 0.46
▸ CA9 Q16790 1/20 0.46
▸ CA13 Q8N1Q1 1/20 0.46
▸ CA14 Q9ULX7 1/20 0.46
▸ CA5B Q9Y2D0 1/20 0.46
▸ TTR P02766 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28217573 0.97 AKR1C4 (0.50) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL17890434 0.88 LCK (0.56) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL71146 0.88 LCK (0.60) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL710220 0.86 LCK (0.48) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL11706863 0.85 LCK (0.58) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL9478732 0.84 AKR1C4 (0.50) AKR1C4AKR1C3AKR1C2AKR1C1PTPN1
SCHEMBL31169213 0.84 AKR1C4 (0.50) AKR1C4AKR1C3AKR1C2AKR1C1LCK
Ethylene SCHEMBL11741498 0.82 LCK (0.56) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL24697741 0.82 KEAP1 (0.45) AKR1C4AKR1C3AKR1C2AKR1C1LCK
SCHEMBL1047232 0.82 KDM4E (0.57) AKR1C4AKR1C3AKR1C2AKR1C1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117402494-A Complex high-strength polyarylene sulfide based composite material and preparation and application thereof 新凝合科技(成都)有限公司 2024-01-16 — — CN claimed
CN-105541850-B A kind of phthalocyanine-like compound and its synthetic method and application 京东方科技集团股份有限公司 2018-05-15 — — CN claimed
CN-105646176-B The preparation method of 4,5 dibromo phthalic acids 郑州轻工业学院 2017-11-24 — — CN claimed
CN-107033152-A A kind of poly phthalocyanine compound, organic field effect tube and preparation method thereof 京东方科技集团股份有限公司 2017-08-11 — — CN claimed
WO-2025136841-A1 SUBSTITUTED ISOQUINOLINE DERIVATIVES AND METHODS OF USE THEREOF MERCK SHARP & DOHME LLC (US) 2025-06-26 — — WO disclosed
CN-119684242-A Method for preparing anhydride by utilizing paraffin oil dehydration 中国科学院化学研究所 2025-03-25 — — CN disclosed
US-12122790-B2 Photoactive compound SUMITOMO CHEMICAL CO., LTD. (JP) 2024-10-22 — — US disclosed
CN-113169281-B Photoactive compounds 住友化学株式会社 2024-10-15 — — CN disclosed
US-20240190880-A1 SMALL MOLECULE DEGRADERS OF ESTROGEN RECEPTOR WITH CEREBLON LIGANDS REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-06-13 — — US disclosed
US-20240150360-A1 Small Molecule Degraders of CBP/p300 Proteins THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-05-09 — — US disclosed
CN-117402494-A Complex high-strength polyarylene sulfide based composite material and preparation and application thereof 新凝合科技(成都)有限公司 2024-01-16 — — CN disclosed
EP-3888150-B1 PHOTOACTIVE COMPOUND SUMITOMO CHEMICAL CO (JP) 2023-01-04 — — EP disclosed
US-20170256725-A1 PHTHALOCYANINE COMPOUND AND SYNTHESIS METHOD AND USE THEREOF BOE TECHNOLOGY GROUP CO., LTD. (CN) 2017-09-07 — — US disclosed
US-20170256725-A1 PHTHALOCYANINE COMPOUND AND SYNTHESIS METHOD AND USE THEREOF BOE TECHNOLOGY GROUP CO., LTD. (CN) 2017-09-07 — — US disclosed
US-20170256725-A1 PHTHALOCYANINE COMPOUND AND SYNTHESIS METHOD AND USE THEREOF BOE TECHNOLOGY GROUP CO., LTD. (CN) 2017-09-07 — — US disclosed
CN-107033152-A A kind of poly phthalocyanine compound, organic field effect tube and preparation method thereof 京东方科技集团股份有限公司 2017-08-11 — — CN disclosed
CN-105646176-A Preparation method of 4,5-dibromophthalic acid 郑州轻工业学院 2016-06-08 — — CN disclosed
CN-105646176-A Preparation method of 4,5-dibromophthalic acid 郑州轻工业学院 2016-06-08 — — CN disclosed
EP-1209172-B1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2008-07-02 — — EP disclosed
US-4002642-A Process for the preparation of polyhalo copper phthalocyanines HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170256725-A1 PHTHALOCYANINE COMPOUND AND SYNTHESIS METHOD AND USE THEREOF PARK7, C1R, C9 AKR1C4 714/4885AKR1C3 353/4885AKR1C2 828/4885
US-20240150360-A1 Small Molecule Degraders of CBP/p300 Proteins EP300, CREBBP, NCOR1 AKR1C4 3442/4885AKR1C3 2740/4885AKR1C2 3125/4885
US-12122790-B2 Photoactive compound CRY1, IK, RPS4Y1 AKR1C4 716/4885AKR1C3 895/4885AKR1C2 1432/4885
US-20240190880-A1 SMALL MOLECULE DEGRADERS OF ESTROGEN RECEPTOR WITH CEREBLON LIGANDS ESR1, CRBN, ESR2 AKR1C4 871/4885AKR1C3 710/4885AKR1C2 756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.