Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675325 | 0.90 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL9325324 | 0.88 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL9327308 | 0.88 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL5517312 | 0.87 | MTNR1A (0.50) | MTNR1AMTNR1BCYP1A2CYP2A6HTR2A | |
| SCHEMBL9325706 | 0.80 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL9676867 | 0.80 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL7236200 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BCYP1A2CYP2A6HTR2A | |
| SCHEMBL7012397 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BCYP1A2CYP2A6HTR2A | |
| SCHEMBL1792288 | 0.78 | MTNR1A (0.49) | MTNR1AMTNR1BCYP1A2CYP2A6HTR2A | |
| SCHEMBL31040507 | 0.78 | MTNR1A (0.49) | MTNR1AMTNR1BCYP1A2CYP2A6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |