Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.53 |
| ▸ | PPARG | P37231 | 13/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.53 |
| ▸ | CETP | P11597 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041857 | 1.00 | PPARA (0.53) | PPARAPPARGPPARDSRRCETP | |
| SCHEMBL8084774 | 1.00 | PPARA (0.53) | PPARAPPARGPPARDSRRCETP | |
| SCHEMBL1165783 | 0.98 | PPARA (0.54) | PPARAPPARGPPARDSRR | |
| SCHEMBL8072578 | 0.94 | PPARA (0.59) | PPARAPPARGPPARDSRR | |
| SCHEMBL7102287 | 0.88 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL7102284 | 0.88 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL6500458 | 0.88 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL4298981 | 0.87 | SRR (0.59) | PPARAPPARGPPARDSRR | |
| SCHEMBL1598729 | 0.87 | SRR (0.47) | PPARAPPARGPPARDSRRCETP | |
| SCHEMBL1598731 | 0.87 | SRR (0.47) | PPARAPPARGPPARDSRRCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208709-A1 | GENETIC SUSCEPTIBILITY VARIANTS ASSOCIATED WITH CARDIOVASCULAR DISEASE | DECODE GENETICS EHF. (IS) | 2012-08-16 | — | — | US | disclosed |
| EP-0276064-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |