SCHEMBL7102329

SCHEMBL7102329

CC1CCN(OCC[Si](C)(C)C)C1=O

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.38
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7103769 0.75
SCHEMBL7632237 0.70
SCHEMBL25808436 0.63 PIK3CD (0.37) PIK3CDCHRM2CHRM4CHRM5CHRM1
SCHEMBL25805922 0.61 PIK3CD (0.35) PIK3CDCHRM2CHRM4CHRM5CHRM1
SCHEMBL14714256 0.61 PABPC1 (0.38) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL15056659 0.60 CYP3A4 (0.36)
SCHEMBL13267478 0.60 TDP1 (0.39)
SCHEMBL26761122 0.60 PIK3CD (0.53) PIK3CDCHRM2CHRM4CHRM5CHRM1
SCHEMBL21389263 0.59 PIK3CD (0.44) PIK3CDCHRM2CHRM4CHRM5CHRM1
SCHEMBL146924 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140952-B1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION BIOAGENCY AG (DE) 2003-09-03 EP disclosed
EP-1140952-A1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION Jomaa Pharmaka GmbH (DE) 2001-10-10 EP disclosed
WO-2000037477-A1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION JOMAA PHARMAKA GMBH (DE) 2000-06-29 WO disclosed