Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | PER2 | O15055 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1093304 | 0.80 | MMP1 (0.37) | PIK3CDALDH1A1MMP1MMP3 | |
| SCHEMBL4989478 | 0.80 | ALDH1A1 (0.36) | PIK3CDALDH1A1MMP1MMP3 | |
| SCHEMBL2687128 | 0.80 | DPP4 (0.42) | PIK3CDALDH1A1MMP1MMP3 | |
| SCHEMBL24471008 | 0.79 | PIK3CD (0.39) | PIK3CDPER2ALDH1A1MMP1MMP3 | |
| SCHEMBL26789326 | 0.79 | PER2 (0.37) | PIK3CDPER2ALDH1A1MMP1MMP3 | |
| SCHEMBL24485369 | 0.79 | MMP1 (0.34) | PIK3CDPER2ALDH1A1MMP1MMP3 | |
| SCHEMBL20894926 | 0.79 | PIK3CD (0.58) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21383815 | 0.77 | PIK3CD (0.56) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL24915557 | 0.77 | PIK3CD (0.56) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21383933 | 0.77 | PIK3CD (0.56) | PIK3CDCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227698-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | PIK3CD 1559/4885CHRM2 701/4885CHRM4 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.