Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101807 | 0.79 | ALOX5 (0.57) | ALOX5HDAC6MAOBACACBFFAR1 | |
| SCHEMBL7097990 | 0.76 | FFAR1 (0.53) | ALOX5HDAC6MAOBFFAR1 | |
| SCHEMBL5880940 | 0.75 | MRGPRX4 (0.44) | MRGPRX4GRM2FFAR1 | |
| SCHEMBL1508420 | 0.72 | FFAR1 (0.73) | FFAR1 | |
| SCHEMBL171861 | 0.71 | MRGPRX4 (0.47) | MRGPRX4MAOBGRM2 | |
| SCHEMBL17141416 | 0.71 | MRGPRX4 (0.54) | MRGPRX4MAOBGRM2 | |
| SCHEMBL26838881 | 0.70 | ALOX5 (0.84) | ALOX5HDAC6 | |
| SCHEMBL11232868 | 0.69 | MAOB (0.62) | MRGPRX4MAOBGRM2 | |
| SCHEMBL2439480 | 0.69 | NPC1 (0.48) | CYP3A4 | |
| SCHEMBL3281426 | 0.69 | MET (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |