Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.70 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | KRAS | P01116 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096493 | 0.91 | ABCG2 (0.70) | ABCG2MAOAAURKAPTPN1NPC1 | |
| SCHEMBL7102265 | 0.85 | ABCG2 (0.86) | ABCG2MAOAAURKAPTPN1MAPT | |
| SCHEMBL4610668 | 0.85 | ABCG2 (0.85) | ABCG2MAOAAURKANPC1ALDH1A1 | |
| SCHEMBL4610666 | 0.85 | ABCG2 (0.85) | ABCG2MAOAAURKANPC1ALDH1A1 | |
| SCHEMBL7099971 | 0.85 | MAPT (0.74) | ABCG2PTPN1NPC1ALDH1A1MAPT | |
| SCHEMBL7100777 | 0.82 | ABCG2 (0.67) | ABCG2MAOAAURKAPTPN1NPC1 | |
| SCHEMBL22721804 | 0.82 | ABCG2 (0.71) | ABCG2PTPN1NPC1ALDH1A1MAPT | |
| SCHEMBL7097534 | 0.82 | ABCG2 (0.71) | ABCG2PTPN1NPC1ALDH1A1MAPT | |
| SCHEMBL29391850 | 0.82 | ABCG2 (0.71) | ABCG2PTPN1NPC1ALDH1A1MAPT | |
| SCHEMBL16597306 | 0.81 | ABCG2 (0.72) | ABCG2MAOANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | claimed |
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | disclosed |