Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.35 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102590 | 0.93 | ST14 (0.40) | ST14PLAUF2ACEF10 | |
| SCHEMBL7104148 | 0.93 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2ST14PLAUF2 | |
| SCHEMBL7102567 | 0.91 | F2 (0.45) | ALDH1A1SMN1; SMN2ST14PLAUF2 | |
| SCHEMBL7102491 | 0.87 | F2 (0.42) | F2ACECAPN1 | |
| SCHEMBL7102500 | 0.85 | F2 (0.51) | ALDH1A1SMN1; SMN2F2F10 | |
| SCHEMBL7105056 | 0.83 | F2 (0.46) | ST14PLAUF2F10HPN | |
| SCHEMBL7102496 | 0.81 | TMPRSS11D (0.44) | SMN1; SMN2ST14PLAUF2MAPT | |
| SCHEMBL7102505 | 0.81 | TMPRSS11D (0.44) | SMN1; SMN2ST14PLAUF2MAPT | |
| SCHEMBL7102587 | 0.79 | TMPRSS11D (0.50) | F2F10PRSS1 | |
| SCHEMBL7102595 | 0.79 | TMPRSS11D (0.50) | F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |