Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | TMPRSS11D | O60235 | 2/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102499 | 0.93 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2F2ACEPLAU | |
| SCHEMBL7102491 | 0.92 | F2 (0.42) | F2ACETMPRSS11DCAPN1 | |
| SCHEMBL7102500 | 0.91 | F2 (0.51) | ALDH1A1SMN1; SMN2F2PLGTMPRSS11D | |
| SCHEMBL7102590 | 0.88 | ST14 (0.40) | F2ACEPLAUST14 | |
| SCHEMBL7102567 | 0.85 | F2 (0.45) | ALDH1A1SMN1; SMN2F2PLGPLAU | |
| SCHEMBL7106036 | 0.82 | F2 (0.53) | F2PLGTMPRSS11D | |
| Hydrochloric Acid SCHEMBL7140906 | 0.82 | F2 (0.54) | F2PLGTMPRSS11D | |
| SCHEMBL7104150 | 0.80 | TMPRSS11D (0.48) | F2PLGTMPRSS11D | |
| SCHEMBL7104147 | 0.80 | TMPRSS11D (0.48) | F2PLGTMPRSS11D | |
| SCHEMBL7105056 | 0.79 | F2 (0.46) | F2PLGPLAUST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |