Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827963 | 0.79 | PLA2G2D (0.63) | NR4A1NR4A2NR4A3PTPN1MMP3 | |
| SCHEMBL29645052 | 0.79 | PLA2G2D (0.63) | NR4A1NR4A2NR4A3PTPN1MMP3 | |
| SCHEMBL5873186 | 0.78 | CNR1 (0.41) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL4598908 | 0.78 | CES2 (0.48) | PTPN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL29035956 | 0.78 | NR4A1 (0.57) | NR4A1NR4A2NR4A3PTPN1MMP3 | |
| SCHEMBL5446678 | 0.77 | ERCC5 (0.41) | ALDH1A1HPGDKMT2AKDM4ELMNA | |
| SCHEMBL28352835 | 0.76 | NR4A1 (0.55) | NR4A1NR4A2NR4A3PTPN1MMP3 | |
| SCHEMBL10357836 | 0.76 | NR4A1 (0.55) | NR4A1NR4A2NR4A3PTPN1MMP3 | |
| SCHEMBL5221184 | 0.75 | PTPN1 (0.67) | NR4A1NR4A2NR4A3PTPN1MMP3 | |
| SCHEMBL31360351 | 0.75 | PTPN1 (0.67) | NR4A1NR4A2NR4A3PTPN1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4857475-A | Labelled and labellable reagents for fluorometric assays | Ekins, Roger Philip (GB) | 1989-08-15 | — | — | US | claimed |
| US-4565790-A | LANTHANIDE SERIES COMPLEX, B-DIKETONE, DETERGENT | WALLAC OY (FI) | 1986-01-21 | — | — | US | claimed |
| US-9017962-B2 | Intracellular reporters | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-04-28 | — | — | US | disclosed |
| EP-1943262-B1 | IRE-1 ALPHA SUBSTRATES | MANNKIND CORP (US) | 2013-01-23 | — | — | EP | disclosed |
| EP-2504423-A1 | MULTI-PURPOSE SUBSTRATES USEFUL FOR CELL CULTURE AND METHODS FOR MAKING AND USING THE SAME | Corning Incorporated (US) | 2012-10-03 | — | — | EP | disclosed |
| US-8252549-B2 | Multi-purpose substrates useful for cell culture and methods for making | CORNING INCORPORATED (US) | 2012-08-28 | — | — | US | disclosed |
| US-8236523-B2 | Camp reporters and high throughput assays | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-08-07 | — | — | US | disclosed |
| US-8124343-B2 | IRE-1α substrates | MANNKIND CORPORATION (US) | 2012-02-28 | — | — | US | disclosed |
| US-8080235-B2 | Protein kinase A reporters useful in high throughput assays | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-12-20 | — | — | US | disclosed |
| WO-2011149743-A1 | MULTIPLY FLUORESCENTLY LABELED CALCIUM PHOSPHATE-PROTEIN SURFACES | CORNING INCORPORATED (US) | 2011-12-01 | — | — | WO | disclosed |
| US-20110287952-A1 | IRE-1alpha SUBSTRATES | MANNKIND CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| WO-2002091493-A2 | ELECTROLUMINESCENT DEVICE | ELAM-T LIMITED (GB) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002090466-A1 | ELECTROLUMINESCENT DEVICES | ELAM-T LIMITED (GB) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002087283-A1 | ELECTROLUMINESCENT DEVICES INCORPORATING MIXED METAL ORGANIC COMPLEXES | ELAM-T LIMITED (GB) | 2002-10-31 | — | — | WO | disclosed |
| WO-2002086015-A2 | MIXED METAL ORGANIC COMPLEXES | ELAM-T LIMITED (GB) | 2002-10-31 | — | — | WO | disclosed |
| WO-2002075820-A1 | ELECTROLUMINESCENT DEVICES | ELAM-T LIMITED (GB) | 2002-09-26 | — | — | WO | disclosed |
| WO-2002043447-A2 | ELECTROLUMINESCENT DEVICE | ELAM-T LIMITED (GB) | 2002-05-30 | — | — | WO | disclosed |
| WO-2002043446-A1 | ELECTROLUMINESCENT DEVICE | ELAM-T LIMIED (GB) | 2002-05-30 | — | — | WO | disclosed |
| WO-2002043444-A2 | ELECTROLUMINESCENT DEVICE | ELAM-T LIMITED (GB) | 2002-05-30 | — | — | WO | disclosed |
| US-20010055776-A1 | High throughput cell-based assay kits | GREENWALT DALE (US) | 2001-12-27 | — | — | US | disclosed |