Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446678 | 0.81 | ERCC5 (0.41) | ALDH1A1ERCC5FEN1GAAKMT2A | |
| SCHEMBL710253 | 0.78 | NR4A1 (0.49) | ALDH1A1ALOX15PTPN1GAAMEN1 | |
| SCHEMBL3948165 | 0.77 | CTSD (0.49) | ALDH1A1GAAKMT2ANPC1HPGD | |
| SCHEMBL361933 | 0.77 | CES1 (0.60) | CES2CES1ALDH1A1ALOX15PTPN1 | |
| SCHEMBL29668746 | 0.77 | CES1 (0.60) | CES2CES1ALDH1A1ALOX15PTPN1 | |
| SCHEMBL583437 | 0.76 | CES1 (0.57) | CES2CES1ALDH1A1ALOX15PTPN1 | |
| SCHEMBL9630805 | 0.74 | CES1 (0.55) | CES2CES1ALDH1A1ALOX15PTPN1 | |
| SCHEMBL9655468 | 0.74 | CES1 (0.55) | CES2CES1ALDH1A1ALOX15PTPN1 | |
| SCHEMBL9565947 | 0.74 | CES1 (0.55) | CES2CES1ALDH1A1ALOX15PTPN1 | |
| SCHEMBL28882937 | 0.73 | KDM4E (0.49) | CES2CES1ALDH1A1ALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008067032-A2 | TRANSGENIC MICE EXPRESSING A REAL-TIME REPORTER FOR CELLULAR CAMP IN A TISSUE-SELECTIVE AND INDUCIBLE MANNER | UNIVERSITY OF MIAMI (US) | 2008-06-05 | — | — | WO | disclosed |
| EP-1907850-A2 | LATERAL FLOW ASSAY AND DEVICE USING MAGNETIC PARTICLES | IDEXX LABORATORIES, INC. (US) | 2008-04-09 | — | — | EP | disclosed |
| EP-1791972-A2 | cAMP REPORTERS | The Johns Hopkins University (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2007050734-A1 | PROTEIN KINASE A REPORTERS USEFUL IN HIGH THROUGHPUT ASSAYS | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007011936-A2 | LATERAL FLOW ASSAY AND DEVICE USING MAGNETIC PARTICLES | IDEXX LABORATORIES, INC. (US) | 2007-01-25 | — | — | WO | disclosed |
| WO-2006023972-A2 | cAMP REPORTERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-03-02 | — | — | WO | disclosed |