SCHEMBL7102535

SCHEMBL7102535

CCOC(=O)CC1(c2ccccc2)C(=O)c2ccccc2C1=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
KMT2A Q03164 4/20 0.64
PKM P14618 1/20 0.64
MAPT P10636 3/20 0.54
GAA P10253 2/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TP53 P04637 1/20 0.49
THRB P10828 1/20 0.49
SLC6A9 P48067 2/20 0.48
MEN1 O00255 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
BRD4 O60885 1/20 0.45
PTPN1 P18031 1/20 0.42
MITF O75030 2/20 0.42
CYP1A2 P05177 1/20 0.42
PPID Q08752 1/20 0.41
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5366931 0.84 ALDH1A1 (0.61) ALDH1A1KMT2APKMMAPTRAB9A
Ethyl Acetate SCHEMBL27466900 0.81 KMT2A (0.54) ALDH1A1KMT2APKMMAPTGAA
SCHEMBL7100909 0.80 KMT2A (0.57) ALDH1A1KMT2APKMMAPTGAA
SCHEMBL21470363 0.79 KMT2A (0.56) ALDH1A1KMT2APKMMAPTGAA
SCHEMBL1219825 0.79 KMT2A (0.74) ALDH1A1KMT2APKMMAPTGAA
SCHEMBL7095821 0.79 KMT2A (1.00) ALDH1A1KMT2APKMMAPTGAA
SCHEMBL21470316 0.78 KMT2A (0.55) ALDH1A1KMT2APKMMAPTGAA
SCHEMBL14592445 0.75 MAPT (0.66) ALDH1A1KMT2APKMMAPTGAA
SCHEMBL21470317 0.74 KMT2A (0.50) ALDH1A1KMT2APKMMAPTGAA
SCHEMBL8710208 0.72 BRD4 (0.48) ALDH1A1KMT2AMAPTGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0764886-B1 Electrophotosensitive material containing a naphthoquinone derivative KYOCERA MITA CORP (JP) 2003-09-03 EP disclosed
US-5994012-A CHARGE GENERATING COMPOUND, CHARGE TRANSFER COMPOUND AND BINDER MITA INDUSTRIAL CO., LTD. (JP) 1999-11-30 US disclosed
US-5863688-A REACTING 1,3-INDANDIONE DERIVATIVE WITH A BROMOACETIC ESTER TO FORM 1,3-INDANDIONE ESTER, ISOMERIZING THE ESTER DERIVATIVE IN PRESENCE OF SODIUM HYDRIDE TO FORM NAPHTHOIC ESTER, OXIDIZING TO FORM NAPHTHOQUINONE DERIVATIVE MITA INDUSTRIAL CO., LTD (JP) 1999-01-26 US disclosed
EP-0764886-A2 Naphthoquinone derivative and electrophotosensitive material using the same MITA INDUSTRIAL CO. LTD. (JP) 1997-03-26 EP disclosed