Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071848 | 0.93 | CYP3A4 (0.42) | MAOBMAOACYP3A4PPARGALOX5 | |
| Trifluoroacetic Acid SCHEMBL709554 | 0.91 | CYP3A4 (0.43) | MAOBMAOACYP3A4PPARGALOX5 | |
| Trifluoroacetic Acid SCHEMBL711595 | 0.87 | LRRK2 (0.43) | CYP3A4PPARGALOX5PSEN1FFAR1 | |
| Trifluoroacetic Acid SCHEMBL712956 | 0.86 | GPR132 (0.45) | PPARGALOX5PSEN1PPARDGPR132 | |
| Trifluoroacetic Acid SCHEMBL713332 | 0.86 | KMT2A (0.41) | CYP3A4GPR132PDE5APDE4APDE4B | |
| Trifluoroacetic Acid SCHEMBL710853 | 0.86 | PPARG (0.39) | MAOBMAOACYP3A4PPARGCHEK2 | |
| Trifluoroacetic Acid SCHEMBL711385 | 0.86 | CYP3A4 (0.39) | MAOBCYP3A4PPARDGPR132CHEK2 | |
| Trifluoroacetic Acid SCHEMBL709855 | 0.84 | SMO (0.41) | MAOBCYP3A4PPARGFFAR1PPARD | |
| Trifluoroacetic Acid SCHEMBL712591 | 0.84 | PDE5A (0.41) | CYP3A4PPARGFFAR1PPARDGPR132 | |
| Trifluoroacetic Acid SCHEMBL711971 | 0.83 | CYP3A4 (0.43) | CYP3A4PDE5APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124617-B2 | Imidazopyridine compounds | TAKEDA SAN DIEGO, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100069431-A1 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA SAN DIEGO, INC. | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069431-A1 | IMIDAZOPYRIDINE COMPOUNDS | GCK, GCKR, KHK | MAOB 1046/4885MAOA 1361/4885CYP3A4 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.