Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213830 | 0.87 | TSHR (0.32) | OPRD1TSHR | |
| SCHEMBL6214453 | 0.83 | OPRD1 (0.31) | OPRD1 | |
| SCHEMBL6212520 | 0.83 | TSHR (0.30) | TSHR | |
| SCHEMBL2103475 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL6214909 | 0.72 | CCNC (0.33) | SLC22A12 | |
| SCHEMBL6215881 | 0.69 | CCNC (0.33) | — | |
| SCHEMBL22075884 | 0.66 | TSHR (0.35) | TSHR | |
| SCHEMBL2626833 | 0.65 | IDH1 (0.31) | — | |
| SCHEMBL16151154 | 0.63 | LOXL2 (0.45) | CASP1SLC22A12 | |
| SCHEMBL224515 | 0.63 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975602-A4 | IMIDAZOLE AND IMIDAZOLINE DERIVATIVES AND USES THEREOF | GRUENENTHAL GMBH (DE) | 2003-01-22 | — | — | EP | disclosed |
| EP-0975602-A1 | IMIDAZOLE AND IMIDAZOLINE DERIVATIVES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046572-A1 | IMIDAZOLE AND IMIDAZOLINE DERIVATIVES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-10-22 | — | — | WO | disclosed |