Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 5/20 | 0.62 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.62 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.41 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.39 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106566 | 0.87 | CYP4F2 (0.45) | CYP4F2CYP4A11CYP4Z1CYP4F11CYP4F12 | |
| SCHEMBL22537802 | 0.86 | HCRTR2 (0.44) | CYP4F2CYP4A11CYP4Z1CA12CA1 | |
| SCHEMBL28703573 | 0.82 | RAB9A (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7448315 | 0.81 | KMT2A (0.49) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL15986419 | 0.80 | MAPT (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL557889 | 0.79 | SMN1; SMN2 (0.55) | CYP4F2CYP4A11CA12CA1CA2 | |
| SCHEMBL8866817 | 0.78 | CYP4F2 (0.57) | CYP4F2CYP4A11CA2PPARAALDH1A1 | |
| SCHEMBL27768012 | 0.78 | CA12 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL29194883 | 0.78 | PPARG (0.51) | ALDH1A1MAPTALOX5NPC1RAB9A | |
| SCHEMBL7105765 | 0.78 | CYP4F2 (0.50) | CYP4F2CYP4A11CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043308-B1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6353025-B1 | COMPOUNDS AS DRUGS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| EP-1043308-A1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |